Incisional and excisional biopsy

Histologic examination revealed a cyst-like structure surrounded by minor salivary gland lobules.  The latter shows evidence of connective tissue fibrosis, chronic inflammation and ductal ectasia (Fig 3).  The cyst-like structure occupies the bulk of the specimen and is large and tortuous.  It is made up of a rim of granulation tissue surrounding a lumen that focally contains mucoid material and foamy macrophages (Fig 2). 

Figure 2 Low power (x100) histology shows a cyst-like structure lined by granulation tissue and filled with mucoid material with sheets of foamy macrophages. 

 

Figure 3 High power (x200) histology shows the lumen of the cyst-like structure filled with mucoid material and foamy macrophages.