Incisional and Excisional Biopsy

Histologic examination revealed a cystic structure with lining epithelium and a supporting fibrous connective tissue wall (Fig 2 & 2a). The latter is focally myxoid with occasional to no inflammatory cells and dilated small blood vessels. The histologic features of the lining epithelium of this cyst are as follow: the epithelium is of variable thickness and is stratified squamous in type. It is interspersed with spaces (microcysts or duct-like spaces without the cuboidal cells lining the spaces). The epithelium is superficially lined by one layer of cuboidal cells interspersed with mucous producing cells (Fig 3) as demonstrated by the special stain (Alcian blue) staining mucous bright blue.

Figure 2 & 2a.  10x magnification demonstrating a cystic structure with lining epithelium and a supporting fibrous connective tissue wall (Fig 2 & 2a). The lining epithelium is stratified squamous in type interspersed with spaces (microcysts or duct-like spaces without the cuboidal cells lining the spaces). The epithelium is superficially lined by one layer of cuboidal cells interspersed with mucous producing cells.

 
Figure 3.  10x magnification demonstrating positive staining for mucin within the spaces in the lining epithelium using Alcian blue special stain for mucin.