Incisional and Excisional Biopsy

Histologic specimens showed small pieces of loose and vascular granulation tissue with clusters of multinucleated giant cells (Fig 3-4). Figure 4 shows two small blood vessels with thick (hyalinized) walls frequently seen in this condition. The histologic diagnosis was rendered by Dr. Kathy Patterson at the Seattle Children’s Hospital, Department of Pathology.

Figure 3.  Low power (x100) histology shows granulation tissue background with many giant cells and clusters of extravasated erythrocytes.

Figure 4. Low power (x100) histology shows granulation tissue with occasional giant cells and hyalinized small blood vessels.