Incisional and excisional biopsy

Histologic examination revealed multiple pieces of myxoid connective tissue devoid of a lining epithelium (Fig 3).   The connective tissue is made up of spindle-shaped and stellate fibroblasts intermixed with short collagen bundles (Fig 4) in most parts and suspended on a myxoid background.  Small blood vessels were scattered throughout the specimen. 

Figure 3. Low power (x100) histology shows a mass of myxoid background with low cellularity, myxoid background intermixed with short collagen bundles consistent with odontogenic myxoma (myxofibroma).

 

Figure 4. High power (x400) histology shows myxoid background, low cellularity and abundant short collagen bundles.