Incisional and excisional biopsy

Histologic examination revealed a piece of soft tissue covered by ulcerated surface epithelium and supported by a mass of granulation tissue containing many giant cells (Figure 3). The latter were of variable shapes and sizes and were haphazardly arranged. Small clusters of hemosiderin pigment were present in the superficial lamina propria (Figure 4). The surface epithelium showed a large ulceration covered by fibrin and neutrophils.

Figure 3. Low power (x100) histology shows a mass of vascular granulation tissue with many multinucleated giant cells.

 

Figure 4. Higher power (x200) histology shows small clusters of hemosiderin pigment in the superficial lamina propria.