Treatment

Under local anesthesia, the exophytic soft tissue lesion was biopsies. The specimen was submitted for microscopic evaluation and the diagnosis led to a referral for complete removal of the exophytic soft tissue and the underlying bony lesion.

Excisional Biopsy

Histologic examination reveals a multisected piece of soft tissue made up of a neoplasm of odontogenic mesenchymal origin. This neoplasm is made up of myxoid fibrous connective tissue with spindle-shaped cells that are haphazardly arranged in most parts (Figure 3). The neoplastic cells are suspended on delicate collagen fibers in some areas and more mature and dense collagen in others (Figure 4). This neoplasm is focally infiltrated by a few lymphocytes.

Figure 3 Low power (x100) H & E histology illustrates myxoid fibrous connective tissue with spindle shaped cells suspended on a delicate background of collagen fibers in most parts and more mature and dense collagen bundles in focal areas.

Figure 4 Higher power (x200) H & E histology illustrates myxoid fibrous connective tissue with spindle shaped cells suspended on a delicate background of collagen fibers in most parts and more mature and dense collagen bundles in focal areas.